Sequence dependence and role of 5'-phosphate in the B to Z transition

Majumder, Kumud ; Brahmachari, Samir K. ; Sasisekharan, V. (1986) Sequence dependence and role of 5'-phosphate in the B to Z transition FEBS Letters, 198 (2). pp. 240-244. ISSN 0014-5793

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001457...

Related URL: http://dx.doi.org/10.1016/0014-5793(86)80413-6

Abstract

Spectroscopic studies on pd(CG)3 and pd(GC)3 have been carried out to elucidate the sequence dependence and effect of free 5'-phosphate on the B to Z transition. Unlike d(CG)3, pd(CG)3 fails to undergo salt-induced B to Z transition at ambient temperature. Model building studies have been carried out to determine the inhibitory role of the 5'-phosphate group, but have been unsuccessful.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Sequence Dependence; Deoxyoligonucleotide; B→Z Transition; 5'-phosphate Effect; Circular Dichroism; Ultraviolet Difference Spectroscopy
ID Code:44510
Deposited On:22 Jun 2011 08:38
Last Modified:18 May 2016 01:08

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