Ajayaghosh, A. ; RajasekharanPillai, V. N. (1996) Photo-triggered selective C-terminal N-methylamidative cleavage of polyethyleneglycol-bound peptides Tetrahedron Letters, 37 (35). pp. 6421-6424. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...
Related URL: http://dx.doi.org/10.1016/0040-4039(96)01363-9
Abstract
A novel liquid-phase method has been designed for the photolytic release of the attached peptides, directly as their C-terminal N-methylamides, under mild conditions in excellent yields and purity. The present approach provides fully side-chain protected peptide N-methylamides, useful for segment condensation and facilitate photo-controlled release of biologically active peptides for therapeutic applications.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 438 |
| Deposited On: | 21 Sep 2010 04:36 |
| Last Modified: | 11 May 2011 10:19 |
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