Issac, B. ; Raghava, G. P. S. (2002) GWFASTA: server for FASTA search in eukaryotic and microbial genomes Biotechniques, 33 (3). pp. 548-556. ISSN 0736-6205
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Abstract
Similarity searches are a powerful method for solving important biological problems such as database scanning, evolutionary studies, gene prediction, and protein structure prediction. FASTA is a widely used sequence comparison tool for rapid database scanning. Here we describe the GWFASTA server that was developed to assist the FASTA user in similarity searches against partially and/or completely sequenced genomes. GWFASTA consists of more than 60 microbial genomes, eight eukaryote genomes, and proteomes of annotatedgenomes. Infact, it provides the maximum number of databases for similarity searching from a single platform. GWFASTA allows the submission of more than one sequence as a single query for a FASTA search. It also provides integrated post-processing of FASTA output, including compositional analysis of proteins, multiple sequences alignment, and phylogenetic analysis. Furthermore, it summarizes the search results organism-wise for prokaryotes and chromosome-wise for eukaryotes. Thus, the integration of different tools for sequence analyses makes GWFASTA a powerful toolfor biologists.
Item Type: | Article |
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Source: | Copyright of this article belongs to Informa plc. |
ID Code: | 43115 |
Deposited On: | 10 Jun 2011 04:58 |
Last Modified: | 18 May 2016 00:12 |
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