Effect of acute and chronic administration of gonadotropin releasing hormone agonist, buserelin, on serum chorionic gonadotropin, oestradiol-17β and progesterone during early pregnancy in the South Indian bonnet monkey (Macaca radiata)

Jagannadha Rao, A. ; Chakraborti, R. (1990) Effect of acute and chronic administration of gonadotropin releasing hormone agonist, buserelin, on serum chorionic gonadotropin, oestradiol-17β and progesterone during early pregnancy in the South Indian bonnet monkey (Macaca radiata) Animal Reproduction Science, 22 (3). pp. 261-269. ISSN 0378-4320

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/037843...

Related URL: http://dx.doi.org/10.1016/0378-4320(90)90067-P

Abstract

The effect of a single injection of 100μg of Buserelin on day 19 of gestation and chronic infusion of Buserelin (2.5 μg/h for 11 days) starting from day 20 of gestation on serum chorionic gonadotropin, progesterone and oestradiol-17β was studied. Serum chorionic gonadotropin levels remained elevated for the first 48 h after the start of infusion of Buserelin. However, following injection of 100 μg of Buserelin there was a significant decrease in both serum progesterone and oestradiol-17β levels. The two treatments had no effect on the course of pregnancy.

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