Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist Buserelin and antagonist CDB 2085 A using osmotic minipumps on testicular function in adult male bonnet monkey (Macaca radiata)

Jagannadha Rao, A. ; Chakraborti, R. ; Kotagi, S. G. ; Ravindranath, N. (1990) Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist Buserelin and antagonist CDB 2085 A using osmotic minipumps on testicular function in adult male bonnet monkey (Macaca radiata) Andrologia, 22 (6). pp. 567-573. ISSN 0303-4569

Full text not available from this repository.

Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-...

Related URL: http://dx.doi.org/10.1111/j.1439-0272.1990.tb02056.x

Abstract

The effect of chronic infusion of gonadotropic hormone agonist Buserelin or antagonist CDB 2085 A for 15 weeks via alzet minipumps in adult male bonnet monkeys was studied. Infusion of Buserelin resulted in a decrease in the difference between serum testosterone values at 22.00 hours and 10.00 hours, decrease in responsiveness to injected Buserelin as judged by change in serum testosterone values from pre-injection values and decrease in sperm counts. Infusion of antagonist resulted in a decrease in the difference between serum testosterone values at 22.00 hours and 10.00 hours.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:GnRH; Constant Infusion; Buserelin; Testicular Function; Testis Function; GnRH
ID Code:43000
Deposited On:09 Jun 2011 04:30
Last Modified:09 Jun 2011 04:30

Repository Staff Only: item control page