Rao, A. J. ; Ramachandra, S. G. ; Ramesh, V. ; Krishnamurthy, H. N. ; Jayaraman, S. ; Gopalakrishnan, K. ; Juneja, H. S. (1998) Effect of chronic administration of tamoxifen on fertility in male bonnet monkeys (Macaca radiata) Andrologia, 30 (3). pp. 129-132. ISSN 0303-4569
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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-...
Related URL: http://dx.doi.org/10.1111/j.1439-0272.1998.tb01388.x
Abstract
Administration of Tamoxifen via the Alzet pump at a rate of 50 μg hr−1 for 90 days in the adult male bonnet monkeys Macaca radiata had no effect on the serum testosterone concentration determined at 10 am and 10 pm as well as total sperm count determined at 15-day intervals over a period of 260 days. However, a significant reduction in sperm motility was observed beyond 90 days up until the 225th day. Breeding studies conducted from day 90 to 260 revealed that these males were infertile.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Tamoxifen; Bonnet Monkey; Fertility; Motility |
| ID Code: | 42990 |
| Deposited On: | 08 Jun 2011 13:24 |
| Last Modified: | 08 Jun 2011 13:24 |
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