Androgen binding protein levels and FSH binding to testicular membranes in vitamin A deficient rats and during subsequent replenishment with vitamin A

Unni, Emmanual ; Rao, M. R. S. (1986) Androgen binding protein levels and FSH binding to testicular membranes in vitamin A deficient rats and during subsequent replenishment with vitamin A Journal of Steroid Biochemistry, 25 (4). pp. 579-583. ISSN 0022-4731

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/002247...

Related URL: http://dx.doi.org/10.1016/0022-4731(86)90406-1

Abstract

ABP levels in the testes and epididymides of vitamin A deficient-retinoic acid maintained rats were only 20 and 6% respectively as compared with those in normal rats. The number of FSH receptors in the testes of vitamin A deficient rats, as measured by [125I]ovine FSH binding to isolated testicular membranes, was only 40% of that in the testes of normal rats. Supplementation of retinyl acetate to these vitamin A deficient rats for 16 days resulted in restoration of the number of FSH receptors to normal levels. On the other hand, ABP levels were restored to 32 and 34% only in the testes and epididymides respectively.

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