Highly chemoselective reduction of aromatic nitro compounds by copper nanoparticles/ammonium formate

Saha, Amit ; Ranu, Brindaban (2008) Highly chemoselective reduction of aromatic nitro compounds by copper nanoparticles/ammonium formate The Journal of Organic Chemistry, 73 (17). pp. 6867-6870. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo800863m

Related URL: http://dx.doi.org/10.1021/jo800863m

Abstract

A highly chemoselective reduction of aromatic nitro compounds to the corresponding amino derivatives has been achieved by a combination of copper nanoparticles and ammonium formate in ethylene glycol at 120°C. The reductions are successfully carried out in presence of a wide variety of other reducible functional groups in the molecule, such as Cl, I, OCH2Ph, NHCH2Ph, COR, COOR, CN, etc. The reactions are very clean and high yielding.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:41449
Deposited On:30 May 2011 05:32
Last Modified:30 May 2011 05:32

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