A practical and green approach towards synthesis of dihydropyrimidinones without any solvent or catalyst

Ranu, Brindaban C. ; Hajra, Alakananda ; Dey, Suvendu S. (2002) A practical and green approach towards synthesis of dihydropyrimidinones without any solvent or catalyst Organic Process Research & Development, 6 (6). 817–818. ISSN 1083-6160

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Official URL: http://pubs.acs.org/doi/abs/10.1021/op0255478

Related URL: http://dx.doi.org/10.1021/op0255478

Abstract

A simple, efficient, green, and cost-effective procedure has been developed for the synthesis of dihydropyrimidinones by a solvent-free and catalyst-free Biginelli's condensation of 1,3-dicarbonyl compound, aldehyde, and urea. This approach of direct reaction in neat without solvent and catalyst shows a new direction in green synthesis.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:41428
Deposited On:30 May 2011 05:14
Last Modified:30 May 2011 05:14

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