Manjula, G. ; Ramakrishnan, C. (1979) Stereochemical studies on cyclic peptides. Part X. Conformational Analysis of Hydrogen Bonded Cyclic Pentapeptides International Journal of Peptide and Protein Research, 13 (3). pp. 353-362. ISSN 0367-8377
Full text not available from this repository.
Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-...
Related URL: http://dx.doi.org/10.1111/j.1399-3011.1979.tb01892.x
Abstract
Conformational aspects of 4→1 hydrogen bonded cyclic pentapeptides are considered in this paper from the point of view of "contact criteria" and potential energy calculations. Three types of such hydrogen bonded conformations, designated A1, A2 and B, are possible, involving some amount of strain on the bond angles. The energy of hydrogen bonded cyclopentaglycyl is somewhat less than that of the five-fold symmetrical conformation. The stereochemical feasibility of introducing L- and D-alanyl residues in these structures has also been studied and the possible types for different sequences of alanyl residues have been determined. The results are discussed further in the light of the limited data available from crystal structure and nuclear magnetic resonance studies on cyclic pentapeptides.
Item Type: | Article |
---|---|
Source: | Copyright of this article belongs to Munksgaard International Publishers. |
Keywords: | Conformation; Cyclic Pentapeptide; Cyclopeptides; Hydrogen Bond; Pentapeptide; Cyclic; Ring Closure; Stereochemistry |
ID Code: | 41008 |
Deposited On: | 26 May 2011 05:57 |
Last Modified: | 23 Sep 2011 04:51 |
Repository Staff Only: item control page