Ramachandran, J. ; Lee, Virginia ; Li, Choh Hao (1972) Stimulation of lipolysis and cyclic AMP accumulation in rabbit fat cells by human growth hormone Biochemical and Biophysical Research Communications, 48 (2). pp. 274-279. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00062...
Related URL: http://dx.doi.org/10.1016/S0006-291X(72)80046-9
Abstract
Human growth hormone (HGH) has been found to produce a rapid stimulation of lipolysis in isolated rabbit fat cells but not in rat adipocytes. The species specificity exhibited by HGH and other evidence strongly suggest that the lipolytic action is an intrinsic property of HGH and not due to contamination with other pituitary lipolytic agents. The stimulation of lipolysis by HGH appears to be mediated by cyclic AMP since the effect of the hormone on both cyclic AMP accumulation and glycerol release are potentiated by theophylline.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 40862 |
| Deposited On: | 25 May 2011 09:17 |
| Last Modified: | 25 May 2011 09:17 |
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