Ramachandran, J. ; Lee, Virginia (1970) Preparation and properties of the o̲-nitrophenyl sulfenyl derivative of ACTH: an inhibitor of the lipolytic action of the hormone Biochemical and Biophysical Research Communications, 38 (3). pp. 507-512. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(70)90743-6
Abstract
Chemical modification of the single tryptophan residue in adrenocorticotropin (ACTH) by reaction with o̲-nitrophenyl sulfenyl chloride results in the loss of the lipolytic activity of the hormone. The lipolytic action of unmodified ACTH is blocked by the o̲-nitrophenyl sulfenyl derivative. The inhibitor has no effect on the action of glucagon on isolated fat cells.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 40840 |
| Deposited On: | 25 May 2011 07:16 |
| Last Modified: | 25 May 2011 07:16 |
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