Basavaiah, Deevi ; Reddy, Raju Jannapu ; Lenin, Dandamudi V. (2010) The Baylis-Hillman adducts as valuable source for one-pot multi-step synthesis: a facile synthesis of substituted piperidin-2-ones Helvetica Chimica Acta, 93 (6). pp. 1180-1186. ISSN 0018-019X
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Official URL: http://www3.interscience.wiley.com/journal/1235257...
Related URL: http://dx.doi.org/10.1002/hlca.200900352
Abstract
A facile, convenient, and one-pot multi-step synthesis of substituted piperidin-2-ones from the Baylis-Hillman alcohols derived from various aldehydes and acrylonitrile, involving Johnson-Claisen rearrangement, reduction of an α, β-unsaturated nitrile moiety into the saturated amine-skeleton, followed by cyclization, in an operationally simple procedure, is described.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
| Keywords: | Baylis-Hillman Adducts; Piperidin-2-ones; Multicomponent Reactions; Johnson-claisen Rearrangement; X-Ray Crystallography |
| ID Code: | 3965 |
| Deposited On: | 13 Oct 2010 07:09 |
| Last Modified: | 17 Jan 2011 04:05 |
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