First example of electrophile induced Baylis-Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives

Basavaiah, Deevi ; Rao, Anumolu Jaganmohan (2003) First example of electrophile induced Baylis-Hillman reaction: a novel facile one-pot synthesis of indolizine derivatives Chemical Communications (5). pp. 604-605. ISSN 1359-7345

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Related URL: http://dx.doi.org/10.1039/b211349

Abstract

Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis-Hillman reaction.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:3928
Deposited On:18 Oct 2010 09:25
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