Sharma, Arun Kumar ; Sharma, Archana (2001) Chromosome painting-principles, strategies and scope Methods in Cell Science, 23 (1-3). pp. 1-5. ISSN 1381-5741
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Official URL: http://www.springerlink.com/content/pp17j56g615870...
Related URL: http://dx.doi.org/10.1023/A:1013108610550
Abstract
Chromosome Painting is emerging as a powerful tool in the exact localization of different gene sequences of chromosomes at the microscopic level. It is principally based on molecular hybridization in situ with sequence specific probes on chromosomes. Different strategies have been adoptedfor the preparation of probes, hybridization and visualization. The impact of this method lies in identification of genes for desired characters in the chromosomes, including those of genetic disorders, in cancer research, in transgenesis and in studies on biodiversity and evolution.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer. |
| Keywords: | Chromosome Painting; Molecular Hybridization |
| ID Code: | 39023 |
| Deposited On: | 06 May 2011 09:22 |
| Last Modified: | 06 May 2011 09:22 |
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