Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem prins and friedel-crafts reactions

Basavaiah, Deevi ; Reddy, Kanumuri Ramesh (2007) Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem prins and friedel-crafts reactions Organic Letters, 9 (1). pp. 57-60. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol062561m

Related URL: http://dx.doi.org/10.1021/ol062561m

Abstract

A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel-Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:3897
Deposited On:18 Oct 2010 09:29
Last Modified:17 Jan 2011 04:29

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