Biswas, Sonali ; Talukder, Geeta ; Sharma, Archana (1997) Selenium salts and chromosome damage Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 390 (3). pp. 201-205. ISSN 1383-5718
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S13835...
Related URL: http://dx.doi.org/10.1016/S1383-5718(97)00004-1
Abstract
Sodium selenite and sodium selenate, fed by gavaging to age-matched male Swiss albino mice and observed after 24 h following a colchicine-fixative-air drying-Giemsa schedule, were found to induce chromosome breaks and spindle disturbances in bone marrow cells. The four concentrations used were fractions of LD50 and the effects were directly proportionate to the concentration of the chemical. Sodium selenite induced a slightly higher frequency of chromosomal aberrations than sodium selenate.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Selenium Toxicity; Chromosome Damage |
| ID Code: | 38958 |
| Deposited On: | 05 May 2011 13:02 |
| Last Modified: | 05 May 2011 13:02 |
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