Giri, Ashok Kumar ; Banerjee, Tara Shankar ; Talukder, Geeta ; Sharma, Archana (1987) Induction of sister chromatid exchange and dominant lethal mutation by 'Katha' (catechu) in male mice Cancer Letters, 36 (2). pp. 189-196. ISSN 0304-3835
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/030438...
Related URL: http://dx.doi.org/10.1016/0304-3835(87)90090-5
Abstract
Induction of sister chromatid exchange (SCE) and dominant lethal mutation by 'Katha' were studied on mice following acute and prolonged oral treatment. A significant increase in SCEs was observed in all the treated series except 1.5 mg/kg body weight treated series when compared to control. Post-implantation loss was also increased by both acute and chronic treatments with 'Katha'. Thus the above results indicate that 'Katha' has a strong clastogenic and mutagenic effect.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 38957 |
| Deposited On: | 05 May 2011 12:57 |
| Last Modified: | 05 May 2011 12:57 |
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