A concise route to biaryls: formal synthesis of biaryl diamino diacid (AB segment) of vancomycin

Rama Rao, A. V. ; Laxma Reddy, K. ; Machender Reddy, M. (1994) A concise route to biaryls: formal synthesis of biaryl diamino diacid (AB segment) of vancomycin Tetrahedron Letters, 35 (28). pp. 5039-5042. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)73314-4

Abstract

An efficient approach to the AB segment of vancomycin involving triphenylphosphine-catalysed coupling of the substituted aryl lithio compound (13) with palladium complex (14) of aromatic Schiff base derived from 3,5-dimethoxybenzaldehyde is described.

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