Dhingra, Narender K. ; Ramamohan, Y. ; Raju, T. R. (1997) Developmental expression of synaptophysin, synapsin I and syntaxin in the rat retina Developmental Brain Research, 102 (2). pp. 267-273. ISSN 0165-3806
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S01653...
Related URL: http://dx.doi.org/10.1016/S0165-3806(97)00085-0
Abstract
Expression of synaptophysin, synapsin I and syntaxin was studied immunocytochemically in the developing rat retina using indirect immunoperoxidase technique. In the inner plexiform layer (IPL), syntaxin immunoreactivity appeared at postnatal day 1 (P1) whereas synaptophysin and synapsin I staining were first observed at P2. In the outer plexiform layer (OPL), synaptophysin appeared at P4, while synapsin I and syntaxin appeared at P8. In the case of synaptophysin, a punctate pattern of staining was observed from the time of its appearance (P4) in the OPL and from P12 onwards in the IPL. Synapsin I and syntaxin immunoreactivity in the OPL were of a low intensity throughout the development and in the adult stage. These findings are discussed in relation to synaptogenesis in the rat retina.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Retina; Development; Synaptophysin; Synapsin I; Syntaxin; Immunocytochemistry; Rat |
| ID Code: | 38510 |
| Deposited On: | 30 Apr 2011 08:51 |
| Last Modified: | 30 Apr 2011 08:51 |
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