Towards chiral diamines as chiral catalytic precursors for the borane-mediated enantioselective reduction of prochiral ketones

Basavaiah, Deevi ; Das, Utpal ; Roy, Suparna (2009) Towards chiral diamines as chiral catalytic precursors for the borane-mediated enantioselective reduction of prochiral ketones Journal of Chemical Sciences, 121 (6). pp. 1003-1010. ISSN 0253-4134

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Official URL: http://www.ias.ac.in/chemsci/Pdf-Nov2009/1003.pdf

Related URL: http://dx.doi.org/10.1007/s12039-009-0112-x

Abstract

Two chiral diamines (3S)-3-anilinomethyl-1,2,3,4-tetrahydroisoquinoline (1) and (2R)-2-anilinomethylpiperidine (2) have been employed as chiral catalytic sources in the borane-mediated asymmetric reduction of prochiral ketones thus providing the resulting secondary alcohols in good enantiomeric purities (up to 81% ee).

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:(3S)-3-Anilinomethyl-1,2,3,4-tetrahydroisoquinoline; (2R)-2-anilinomethylpiperidine; (S)-phenylalanine; Asymmetric Reduction
ID Code:3847
Deposited On:18 Oct 2010 09:37
Last Modified:16 May 2016 14:34

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