Sinha, Neelima ; Jain, Sanjay ; Anand, Nitya (2005) A novel and unusual method for C-N bond formation in 1-substituted-pyrrolidin-2-ones Tetrahedron Letters, 46 (1). pp. 153-156. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2004.10.162
Abstract
A novel 5-C-N bond forming reaction is reported, which involves heating 1-substituted-pyrrolidin-2-ones with cyclic amines in the presence of a base. This reaction provides a convenient method for the synthesis of 1,5-disubstituted-pyrrolidin-2-ones.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | 1-Substituted-pyrrolidin-2-ones; 5-C-N Bond Formation; 1,5-Disubstituted-pyrrolidin-2-ones; Formylation; 1, 3-Disubstituted-pyrrolidin-2-ones |
| ID Code: | 3806 |
| Deposited On: | 18 Oct 2010 09:44 |
| Last Modified: | 03 Jan 2011 10:46 |
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