Nencki’s reaction with cresols

Beri, R. M. ; Gakhar, K. L. ; Rao, P. S. (1951) Nencki’s reaction with cresols Proceedings of the Indian Academy of Sciences, Section A, 33 (2). pp. 88-91. ISSN 0370-0089

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The condensation of cresols with acetic, propionic and butyric acids was tried under conditions of Nencki’s reaction employing anhydrous zinc chloride as the condensing agent. Only o-cresol gave rise to both the ortho- and para-substituted derivatives, while the m- and the p-cresols produced only the ortho-substituted products. The yields varied with the duration of heating.

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