Munshi, Anupama ; Mehrotra, Raj ; Ramesh, Rajagopal ; Panda, Subrat K. (1993) Evaluation of anti-hepadnavirus activity of Phyllanthus amarus and Phyllanthus maderaspatensis in duck hepatitis B virus carrier Pekin ducks Journal of Medical Virology, 41 (4). pp. 275-281. ISSN 0146-6615
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Official URL: http://www3.interscience.wiley.com/journal/1121923...
Related URL: http://dx.doi.org/10.1002/jmv.1890410404
Abstract
Extracts of the two traditional Indian herbs, Phyl lanthus amarus (P. amarus) and Phyllanthus maderaspatensis (P. maderaspatensis), described by others as useful in the treatment of chronic hepatitis B virus infection were studied for antiviral properties on duck hepatitis B virus infection. One hundred and fourteen ducks infected posthatch with the duck hepatitis B virus (DHBV) were divided into groups at three months of age and treated intraperitoneally with the aqueous, butanol, and alcoholic extracts of these two plants at doses of 25, 50, or 200 mg/kg body weight. Saline-treated animals served as controls. In the ducks negative for DHBV in serum after treatment, we observed replicative intermediates in the liver. There was no definite antiviral property observed in the treated ducks.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | DHBV; Antiviral Treatment; Carrier; Dot Hybridisation; Southern Hybridisation |
| ID Code: | 36374 |
| Deposited On: | 05 Jul 2011 10:57 |
| Last Modified: | 05 Jul 2011 10:57 |
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