Prakash, R. K. ; Netrawali, M. S. ; Pradhan, D. S. ; Sreenivasan, A. (1975) Ineffectiveness of rifampicin in inhibiting RNA synthesis in Escherichia coli and T4-infected Escherichia coli cells after exposure to ultraviolet radiation Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 383 (4). pp. 435-440. ISSN 0005-2787
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000527...
Related URL: http://dx.doi.org/10.1016/0005-2787(75)90313-5
Abstract
Residual RNA synthesis in Escherichia coli cells and T4-infected E. coli cells exposed to ultraviolet radiation is insensitive to rifampicin. On the other hand, residual RNA synthesis in these cells after gamma irradiation is further inhibited by rifampicin. The specific effect exerted by ultraviolet irradiation on transcription seems to arise from alterations in the DNA structure rather than in bacterial RNA polymerase since RNA synthesis in ultraviolet-irradiated E. coli cells infected with unirradiated T4 is sensitive to rifampicin.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 35622 |
| Deposited On: | 21 Apr 2011 13:52 |
| Last Modified: | 21 Apr 2011 13:52 |
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