Seshadri, T. R. ; Suryaprakasa Rao, P. (1937) Reactivity of the double bond in coumarins and related α-β unsaturated carbonyl compounds Part IV. Action of bromine on coumaric acids Proceedings of the Indian Academy of Sciences, Section A, 6 (4). pp. 238-242. ISSN 0370-0089
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Official URL: http://www.ias.ac.in/j_archive/proca/6/4/238-242/v...
Related URL: http://dx.doi.org/10.1007/BF03051489
Abstract
By the action of bromine on coumaric, 4-methylcoumaric and 5-nitrocoumaric acids in boiling glacial acetic acid solution 3:6:8-tribromocoumarin, 3:6:8-tribromo-7-methylcoumarin and 3:8-dibromo-6-nitrocoumarin have been obtained in good yield. The primary products are the dibromides of the bromo-compounds produced by the addition at the double bond, subsequent substitution in the nucleus and final ring closure. Hydrogen bromide gets slowly removed during the boiling and during the subsequent crystallisations so as to yield the above-mentioned bromocoumarins. The best method for this however is to use cold alcoholic potash. Small quantities of the lower bromination products are also produced as by-products.
Item Type: | Article |
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Source: | Copyright of this article belongs to Indian Academy of Sciences. |
ID Code: | 35620 |
Deposited On: | 17 Apr 2011 13:17 |
Last Modified: | 17 May 2016 18:35 |
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