Effect of phenethyl alcohol on induction of alkaline phosphatase in Escherichia coli

Tribhuvan, R. C. ; Pilgaokar, A. K. ; Pradhan, D. S. ; Sreenivasan, A. (1970) Effect of phenethyl alcohol on induction of alkaline phosphatase in Escherichia coli Biochemical and Biophysical Research Communications, 41 (1). pp. 244-250. ISSN 0006-291X

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...

Related URL: http://dx.doi.org/10.1016/0006-291X(70)90495-X

Abstract

Phenethyl alcohol, at concentration of 0.15 to 0.2%, specifically inhibits induced formation of alkaline phosphatase activity, but not that of β-galactosidase in Escherichia coli. This inhibition is reversible. Evidence has been obtained which suggests that this chemical prevents conversion of inactive monomer sub-units to active alkaline phosphatase dimer rather than inhibiting de novo synthesis of sub-units themselves.

Item Type:Article
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ID Code:35460
Deposited On:21 Apr 2011 13:37
Last Modified:21 Apr 2011 13:37

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