Katyare, S. S. ; Fatterpaker, P. ; Sreenivasan, A. (1971) Effect of 2, 4-dinitrophenol (DNP) on oxidative phosphorylation in rat liver mitochondria Archives of Biochemistry and Biophysics, 144 (1). pp. 209-215. ISSN 0003-9861
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000398...
Related URL: http://dx.doi.org/10.1016/0003-9861(71)90470-X
Abstract
The effects of a range of DNP concentrations on ADP/O ratio, respiratory control index (RCI), and stimulation of latent ATPase activity of mitochondria have been studied using various substrates. The first and third sites of phosphorylation were found to be more sensitive to DNP action as compared to the second site. No correlation could be seen between any of the three parameters studied. Fluoride was inhibitory to the stimulation of ATPase by DNP only in presence of high concentrations of DNP, but had no inhibitory effect at low DNP concentrations. The inhibitory effects of fluoride and substrates were not additive.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 35422 |
| Deposited On: | 21 Apr 2011 13:39 |
| Last Modified: | 21 Apr 2011 13:39 |
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