Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of Core β-alanyl ureylene retro-bispeptides (MeO---A_aa---[NH---CO---NH]---CH₂---CH₂---CO---NH---A_aa---OMe; A_aa = amino acid A)

Ranganathan, Darshan ; Kurur, Sunita ; Madhusudanan, K. P. ; Karle, Isabella L. (1997) Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of Core β-alanyl ureylene retro-bispeptides (MeO---A_aa---[NH---CO---NH]---CH₂---CH₂---CO---NH---A_aa---OMe; A_aa = amino acid A) Tetrahedron Letters, 38 (26). pp. 4659-4662. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(97)00960-X

Abstract

A novel family of urea-based peptidomimetics containing β-alanyl unit at the core has been synthesized by a simple one-step procedure. Solid state structures of some representative examples have shown self-assembly into highly ordered, extended hydrogen-bonded chains and ribbons with modest NLO activity.

Item Type:	Article
Source:	Copyright of this article belongs to Elsevier Science.
ID Code:	35403
Deposited On:	17 May 2011 10:24
Last Modified:	17 May 2011 10:24

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Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of Core β-alanyl ureylene retro-bispeptides (MeO---Aaa---[NH---CO---NH]---CH2---CH2---CO---NH---Aaa---OMe; Aaa = amino acid A)

Abstract

Self-assembling urea-based peptidomimetics: A simple one-step synthesis and crystal structure of Core β-alanyl ureylene retro-bispeptides (MeO---A_aa---[NH---CO---NH]---CH₂---CH₂---CO---NH---A_aa---OMe; A_aa = amino acid A)