A simple and convenient route to 11-desoxyprostaglandins

Ranganathan, S. ; Ranganathan, D. ; Iyengar, R. (1976) A simple and convenient route to 11-desoxyprostaglandins Tetrahedron, 32 (8). pp. 961-964. ISSN 0040-4020

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/004040...

Related URL: http://dx.doi.org/10.1016/0040-4020(76)85057-0

Abstract

A high yield, four-step route to the key prostaglandin intermediate 4 is described which should make 11-desoxyprostaglandins and their analogs more readily accessible. Procedure provided for the highly versatile 5-benzyloxymethylcyclopentadiene-nitroethylene adduct (1) would enable the preparation of PGA2, the Corey prostaglandin intermediate and syn-7-benzyloxymethylnorbornenone that is related to all the primary prostaglandins.

Item Type:Article
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ID Code:35401
Deposited On:17 May 2011 09:50
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