Design, synthesis, and ion-transport properties of a novel family of cyclic, adamantane-containing cystine peptides

Ranganathan, Darshan ; Haridas, V. ; Madhusudanan, K. P. ; Roy, Raja ; Nagaraj, R. ; John, G. B. ; Sukhaswami, M. B. (1996) Design, synthesis, and ion-transport properties of a novel family of cyclic, adamantane-containing cystine peptides Angewandte Chemie International Edition, 35 (10). pp. 1105-1107. ISSN 1433-7851

Full text not available from this repository.

Official URL: http://onlinelibrary.wiley.com/doi/10.1002/anie.19...

Related URL: http://dx.doi.org/10.1002/anie.199611051

Abstract

A one-step synthesis provided the cyclopeptides 1 - 4 (n= 2 - 5) composed of repeating adamantane and L-cystine units. These macrocycles assume a cavitand-like conformation, in which the interior is hydrophilic and the periphery hydrophobic. Consequently, they can transport Na+ and K+ ions selectively in model membranes.

Item Type:Article
Source:Copyright if this article belongs to John Wiley and Sons, Inc.
Keywords:Adamantanes; Cyclopeptides; Ion Transport
ID Code:35398
Deposited On:17 May 2011 10:04
Last Modified:12 Jul 2012 08:37

Repository Staff Only: item control page