Ranganathan, Darshan ; Haridas, V. ; Madhusudanan, K. P. ; Roy, Raja ; Nagaraj, R. ; John, G. B. ; Sukhaswami, M. B. (1996) Design, synthesis, and ion-transport properties of a novel family of cyclic, adamantane-containing cystine peptides Angewandte Chemie International Edition, 35 (10). pp. 1105-1107. ISSN 1433-7851
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/anie.19...
Related URL: http://dx.doi.org/10.1002/anie.199611051
Abstract
A one-step synthesis provided the cyclopeptides 1 - 4 (n= 2 - 5) composed of repeating adamantane and L-cystine units. These macrocycles assume a cavitand-like conformation, in which the interior is hydrophilic and the periphery hydrophobic. Consequently, they can transport Na+ and K+ ions selectively in model membranes.
Item Type: | Article |
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Source: | Copyright if this article belongs to John Wiley and Sons, Inc. |
Keywords: | Adamantanes; Cyclopeptides; Ion Transport |
ID Code: | 35398 |
Deposited On: | 17 May 2011 10:04 |
Last Modified: | 12 Jul 2012 08:37 |
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