Hamid, Q. Anwar ; Thanumalayan, Subramonian ; Parnaik, Veena K. (1996) An improved method to distinguish micrococcal nuclease sensitivity of chromatin Journal of Biochemical and Biophysical Methods, 33 (1). pp. 59-64. ISSN 0165-022X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/016502...
Related URL: http://dx.doi.org/10.1016/0165-022X(96)00014-0
Abstract
The resolution of the standard micrococcal nuclease assay for sensitivity of active chromatin has been enhanced by the inclusion of an additional step of digesting nuclease-digested DNA with a suitable restriction enzyme prior to Southern hybridization. The improved assay has been used to analyze the chromatin structure of the lamin A, albumin and α-fetoprotein genes during rat liver development.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Micrococcal Nuclease; Active Chromatin; Lamin A; Nuclear Lamina |
| ID Code: | 34819 |
| Deposited On: | 11 Apr 2011 14:03 |
| Last Modified: | 11 Apr 2011 14:03 |
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