Pandey, Siyaram ; Parnaik, Veena K. (1991) Developmental changes in the organization of the nuclear lamina in mouse liver Biochemical and Biophysical Research Communications, 179 (2). pp. 1082-1087. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(91)91930-B
Abstract
We have compared the organization of the nuclear lamina in adult and fetal mouse liver. Western blot analysis of the expression of lamins with specific antibodies indicates that lamin B is expressed throughout liver development, unlike lamins A and C which are absent in fetal liver. Using [125I]lamin in blot binding assays, we have observed that lamin B binds to at least three membrane proteins (96, 54 and 34 kDa) and to lamins A and C in adult nuclear envelopes, but only to the 54 and 34 kDa proteins and lamin B itself in fetal nuclear envelopes, where lamin B appears to be hyperphosphorylated.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 34802 |
| Deposited On: | 11 Apr 2011 14:00 |
| Last Modified: | 11 Apr 2011 14:00 |
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