Reddy, K. R. S. ; Srimannarayana, G. ; Subba Rao, N. V. (1975) Search for physiologically active compounds. Part XXVII. Synthesis of 2-[4-(1, 3-diphenyl)-pyrazolyl]-3-methoxychromones Proceedings of the Indian Academy of Sciences, Section A, 81 (5). pp. 197-203. ISSN 0370-0089
![]()
|
PDF
- Publisher Version
828kB |
Official URL: http://www.ias.ac.in/j_archive/proca/81/5/197-203/...
Related URL: http://dx.doi.org/10.1007/BF03051142
Abstract
The synthesis of 2-[4-(1, 3-diphenyl)-pyrazolyl]-3-hydroxychromones has been carried out by AFO oxidation of 2-hydroxy-[4-(1, 3-diphenyl)-pyrazolylidine)-acetophenones. The pyrazolylidine acetophenones have been prepared by the condensation of o-hydroxyacetophenones with 1, 3-diphenyl-pyrazoIe-4-carboxaldehyde under alkaline conditions. The 3-hydroxy chromones have been converted to their methyl ethers for testing their physiological properties. The structures of these compounds have been established by their analytical and spectral characteristics. All the compounds have been tested against bacteria and fungi and among them, 2-[4-(1, 3-diphenyl]-pyrazolyl)-3-methoxy chromone is found to be active at 20 ppm against Bacillus subtilis.
Item Type: | Article |
---|---|
Source: | Copyright of this article belongs to Indian Academy of Sciences. |
ID Code: | 33731 |
Deposited On: | 30 Mar 2011 12:30 |
Last Modified: | 17 May 2016 16:37 |
Repository Staff Only: item control page