Prasad-Sinha, Jayashree ; Mukherjee, A. S. (1985) Cellular autonomy of hyperactivity in segmental X chromosomal aneuploids of Drosophila and dosage compensation Genetical Research, 46 (1). pp. 19-29. ISSN 0016-6723
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Related URL: http://dx.doi.org/10.1017/S0016672300022424
Abstract
Transcription in 9A–11A aneuploid mosaic female larvae of Drosophila melanogaster has been assessed autoradiographically. Eleven larvae were found to exhibit mosaicism out of sixty-six larvae scanned and the percentage of XO and XX nuclei varied from approximately 9 to 100. Irrespective of the number of XX nuclei present the XO nuclei (duplicated for 9A–11A) invariably showed hyperactivity for both the segments. The XX nucleus exhibited a dosage effect for all the three segments of 9A–11A. Results support the transcriptional constancy of the entire X chromosome, as proposed by Maroni and Lucchesi. Cellular autonomy of hyperactivity of the single X chromosome even at the level of segments of the X is thus evident from the present results.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Cambridge University Press. |
| ID Code: | 32650 |
| Deposited On: | 18 Mar 2011 13:43 |
| Last Modified: | 10 Jun 2011 09:45 |
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