Mahimkar, Manoj B. ; Bhisey, Rajani A. (1995) Occupational exposure to bidi tobacco increases chromosomal aberrations in tobacco processors Mutation Research/Environmental Mutagenesis and Related Subjects, 334 (2). pp. 139-144. ISSN 0165-1161
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/016511...
Related URL: http://dx.doi.org/10.1016/0165-1161(95)90004-7
Abstract
In India, workers engaged in processing of tobacco for the manufacture of bidis (the indogenous substitute for cigarettes) are chronically exposed to tobacco flakes and dust via the cutaneous and nasopharyngeal routes. Hence, workers in a tobacco processing factory were monitored for chromosomal aberrations (CA) using peripheral blood lymphocytes as the test system. Cytogenetic analysis revealed a significant increase in deletion fragments and chromatid gaps in the exposed group. The frequency of aberrant metaphases and the proportion of individuals with CA were significantly higher in workers than in controls, indicating that occupational exposure to tobacco imposes considerable genotoxicity among tobacco processors.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Smokeless Tobacco; Occupational Exposure; Chromosomal Aberrations |
ID Code: | 3229 |
Deposited On: | 11 Oct 2010 09:56 |
Last Modified: | 27 May 2011 09:23 |
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