Studies on tumour inhibitory activity of indigenous drugs: Part I. Tumour inhibitory activity of Hippophae salicifolia, D.DON

Abstract

The extracts of the bark of Hippophae salicifolia D.DON have been found to possess significant inhibitory activity on mouse fibrosarcoma. The tumour tissues showed that there was a degeneration and even necrosis of tumour calls. The alcoholic extract (B) of the bark also possesses an inhibitory activity against Yoshida sarcoma (ascites), as evidenced by the increase in survival period of the experimental animals. The chemistry of the bark is under investigation.