Toxicity of n-hexane and 2,5-hexanediol to the haemopoietic system: a preliminary report

Goel, S. K. ; Rao, G. S. ; Krishna Murti, C. R. (1987) Toxicity of n-hexane and 2,5-hexanediol to the haemopoietic system: a preliminary report Xenobiotica, 17 (2). pp. 217-222. ISSN 0049-8254

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Official URL: http://informahealthcare.com/doi/abs/10.3109/00498...

Related URL: http://dx.doi.org/10.3109/00498258709043931

Abstract

The effect of n-hexane and its metabolite, 2,5-hexanediol, on the haemopoietic system has been investigated in the rat. 2. 59Fe uptake was decreased in the bone marrow of n-hexane-treated animals. 3. Spleen and bone marrow were the target sites for the metabolite 2,5-hexanediol, whereas n-hexane as such does not affect these organs.

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