A total synthesis of the epoxyquinone based antifungal natural product (±)- ambuic acid

Mehta, Goverdhan ; Pan, Subhas Chandra (2005) A total synthesis of the epoxyquinone based antifungal natural product (±)- ambuic acid Tetrahedron Letters, 46 (17). pp. 3045-3048. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2005.03.019

Abstract

A total synthesis of the recently isolated polyketide natural product (±)-ambuic acid has been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and 2-allyl-p-benzoquinone through a simple sequence with sound stereocontrol.

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