Mehta, Goverdhan ; Islam, Kabirul (2000) An eventful synthetic approach towards the biologically potent natural product ottelione A: enantio-, regio- and stereoselective construction of the bicyclic core Synlett, 2000 (10). pp. 1473-1475. ISSN 0936-5214
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Official URL: https://www.thieme-connect.com/ejournals/abstract/...
Related URL: http://dx.doi.org/10.1055/s-2000-7630
Abstract
A novel synthetic approach towards the recently reported anti-tumor and anti-tuberculor natural product ottelione A from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone is delineated. Our short strategy, besides being enantio-, regio- and stereoselective, charts an eventful course and is inherently well-suited for adaptation towards diverse synthetic analogues of this biologically potent natural product.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Thieme Medical Publishers Inc. |
| Keywords: | Antitumor Agents; Enantiomeric Resolution; Stereoselective Synthesis; Wittig Reactions; Intramolecular Cannizzaro Reaction |
| ID Code: | 29271 |
| Deposited On: | 17 Dec 2010 08:18 |
| Last Modified: | 17 Dec 2010 08:18 |
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