Total synthesis of the Novel Antifungal Agent (±)- Jesterone

Mehta, Goverdhan ; Pan, Subhas Chandra (2004) Total synthesis of the Novel Antifungal Agent (±)- Jesterone Organic Letters, 6 (5). pp. 811-813. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol0499699

Related URL: http://dx.doi.org/10.1021/ol0499699

Abstract

A total synthesis of the novel, biologically active epoxyquinone natural product (±)-jesterone has been accomplished from the readily accessible Diels-Alder adduct of cyclopentadiene and prenylated-p-benzoquinone. The approach delineated here is notable for its conceptual simplicity and efficient orchestration of a series of chemo-, regio-, and stereoselective operations.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:29243
Deposited On:17 Dec 2010 08:20
Last Modified:02 Mar 2011 06:18

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