Mehta, Goverdhan ; Robindro Singh, S. (2006) Total synthesis of (±)- Merrilactone A Angewandte Chemie International Edition, 118 (6). pp. 953-955. ISSN 1433-7851
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/anie.20...
Related URL: http://dx.doi.org/10.1002/ange.200503618
Abstract
Merrily, merrily: A total synthesis of the pentacyclic sesquiterpenoid merrilactone A starting from 2,3-dimethyl-2-cyclopentene-1,4-dione has been achieved with good stereo- and regioselectivity. Merrilactone A exhibits impressive neurotrophic activity and may be important for the development of therapeutic drugs for neurodegenerative disorders.
Item Type: | Article |
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Source: | Copyright of this article belongs to John Wiley and Sons, Inc. |
Keywords: | Diastereoselectivity; Natural Products; Neurotrophic Agents; Terpenoids; Total Synthesis |
ID Code: | 28954 |
Deposited On: | 18 Dec 2010 05:46 |
Last Modified: | 01 Mar 2011 11:32 |
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