Total synthesis of the novel angiogenesis inhibitors epoxyquinols A and B

Mehta, Goverdhan ; Islam, Kabirul (2003) Total synthesis of the novel angiogenesis inhibitors epoxyquinols A and B Tetrahedron Letters, 44 (17). pp. 3569-3572. ISSN 0040-4039

[img]
Preview
PDF - Publisher Version
4MB

Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(03)00621-X

Abstract

The synthesis of the recently discovered angiogenesis inhibitors epoxyquinols A and B, having novel polyketide derived dimeric structures, has been accomplished from the readily available Diels-Alder adduct of cyclopentadiene and p-benzoquinone through a short, simple and flexible strategy that is diversity oriented and can be adapted to an asymmetric variant.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:28941
Deposited On:18 Dec 2010 05:47
Last Modified:17 May 2016 11:56

Repository Staff Only: item control page