Munavar, M. Hussain ; Madhavi, K. ; Jayaraman, R. (1993) Aberrant transcriptionin fit mutants ofEscherichia coli and its alleviation by suppressor mutations Journal of Biosciences, 18 (1). pp. 37-45. ISSN 0250-5991
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Official URL: http://www.ias.ac.in/jarch/jbiosci/18/37-45.pdf
Related URL: http://dx.doi.org/10.1007/BF02703036
Abstract
Earlier work from this laboratory had identified, mapped and characterised an intragenic suppressor(fitA24) as well as an extragenic suppressor(fitB) for the temperature-sensitive transcription defective mutationfitA76 inEscherichia coli In this communication we report the results of experiments on RNA synthesis and decay of pulse labelled RNA in strains harbouringfit A76,fitB, fitA24, fitA76-fitA24, fitA76-fitB mutation(s) as well as in the isogenicfitA + fitB+ strain. Taken together with earlier results, this indicates that thefitA andfitB gene products could be involved in the expression of some classes of genes including genes coding for ribosomal proteins. The implications of these results for thein vivo control of transcription inEscherichia coli are discussed.
Item Type: | Article |
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Source: | Copyright of this article belongs to Indian Academy of Sciences. |
Keywords: | fitA; fitB; RNA polymerase; Transcription; Transcription control |
ID Code: | 28500 |
Deposited On: | 15 Dec 2010 11:58 |
Last Modified: | 17 May 2016 11:36 |
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