Hypersensitivity reactions in monkeys immunized with Pr-β-HCG-TT

Indira Nath, ; Dubey, S. K. ; Talwar, Gursaran Parshad (1976) Hypersensitivity reactions in monkeys immunized with Pr-β-HCG-TT Contraception, 13 (2). pp. 231-236. ISSN 0010-7824

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001078...

Related URL: http://dx.doi.org/10.1016/0010-7824(76)90036-6

Abstract

13 rhesus monkeys were immunised with the beta-subunit of HCG or its fragments conjugated with tetanus toxoid or haptens for periods of 3 to 12 months. Of these, 9 monkeys had been given the tetanus toxoid conjugates. Immediate, Arthus and delayed type of hypersensitivity skin reactions to intradermal HCG were found to be negative in all the animals. However, 2 of the hyperimmunized monkeys in which complete Freund's adjuvant was used, showed delayed hypersensitivity skin reactions when challenged with tetanus toxoid.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:27601
Deposited On:10 Dec 2010 11:59
Last Modified:03 Jun 2011 04:24

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