An orphangyr B in the Mycobacterium smegmatis genome uncovered by comparative genomics

Jain, P. ; Nagaraja, V. (2002) An orphangyr B in the Mycobacterium smegmatis genome uncovered by comparative genomics Journal of Genetics, 81 (3). pp. 105-110. ISSN 0022-1333

[img]
Preview
PDF - Publisher Version
173kB

Official URL: http://www.ias.ac.in/jgenet/Vol81No3/105.pdf

Related URL: http://dx.doi.org/10.1007/BF02715907

Abstract

DNA gyrase is an essential topoisomerase found in all bacteria. It is encoded by gyrB and gyrA genes. These genes are organized differently in different bacteria. Direct comparison of Mycobacterium tuberculosis and Mycobacterium smegmatis genomes reveals presence of an additionalgyr B in M. smegmatis flanked by novel genes. Analysis of the amino acid sequence of GyrB from different organisms suggests that the orphan GyrB in M. smegmatis may have an important cellular role.

Item Type:Article
Source:Copyright of this article belongs to Indian Academy of Sciences.
Keywords:Mycobacterium Smegmatis; gyr Genes; DNA Gyrase; Topoisomerase; Comparative Genomics
ID Code:27006
Deposited On:08 Dec 2010 12:52
Last Modified:17 May 2016 10:18

Repository Staff Only: item control page