PTRF triggers a cave in

Mayor, Satyajit ; Chadda, Rahul (2008) PTRF triggers a cave in Cell, 132 (1). pp. 23-24. ISSN 0092-8674

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00928...

Related URL: http://dx.doi.org/10.1016/j.cell.2007.12.021

Abstract

Caveolae are small membrane invaginations important for cell signaling that are characterized by the presence of caveolin proteins. Hill et al. (2008) have now identified PTRF as a new constituent of the caveolar coat. In the absence of PTRF, caveolae flatten and caveolin-1 is released into the cell membrane, where it is rapidly internalized and degraded.

Item Type:Article
Source:Copyright of this article belongs to Cell Press Inc.
ID Code:26707
Deposited On:08 Dec 2010 13:21
Last Modified:17 May 2016 10:00

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