Bhattacharyya, B. ; Wolff, J. (1976) Stabilization of microtubules by lithium ion Biochemical and Biophysical Research Communications, 73 (2). pp. 383-390. ISSN 0006-291X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/000629...
Related URL: http://dx.doi.org/10.1016/0006-291X(76)90719-1
Abstract
Lithium ion, in concentrations of 0.2 - 1.0 mM, promotes tubulin polymerization, provided small concentrations of Mg++ ion are present. This effect of lithium on polymerization, at suboptimal concentration of magnesium, is additive for the two metal ions. Both Li+ and Mg++ protect microtubules against the depolymerizing effects of colchicine or vinblastine.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 26312 |
| Deposited On: | 06 Dec 2010 12:44 |
| Last Modified: | 18 May 2011 07:05 |
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