Naqvi, Afsar Raza ; Choudhury, Nirupam Roy ; Rizwanul Haq, Qazi Mohd. ; Mukherjee, Sunil Kumar (2008) MicroRNAs as biomarkers in tomato leaf curl virus (ToLCV) disease Nucleic Acids Symposium Series, 52 (1). pp. 507-508. ISSN 0261-3166
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Official URL: http://nass.oxfordjournals.org/content/52/1/507.ab...
Related URL: http://dx.doi.org/10.1093/nass/nrn257
Abstract
MicroRNAs are ∼21- 25 nt long RNA species that are critical regulators of transcriptome across theeukaryotes. Growing number of evidences clearly supports their involvement in plant leaf development. ToLCV infection severely affects the morphology of mature tomato leaves. To investigate the mechanism underlying the virus- host interaction, we focussed our studies on expression of microRNAs and the irrespective targets under normal and ToLCV infection. We have cloned Myb33, ARF4 homolog, Argonaute1, Apetala2, SBP transcription factor and RBOH from tomato and checked their expression by RT-PCR. Our work suggests that miR159 is upregulated while miR164 and miR171 are downregulated under viral infection. Our studies shed light on the impact of ToLCV infection on host transcriptome.
Item Type: | Article |
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Source: | Copyright of this article belongs to Oxford University Press. |
ID Code: | 25494 |
Deposited On: | 06 Dec 2010 13:19 |
Last Modified: | 17 May 2016 08:58 |
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