On the fixation probability of a gene under random fluctuations in selection intensities in small populations

Narain, Prem ; Pollak, Edward (1977) On the fixation probability of a gene under random fluctuations in selection intensities in small populations Genetical Research, 29 (2). pp. 113-121. ISSN 0016-6723

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Official URL: http://journals.cambridge.org/abstract_S0016672300...

Related URL: http://dx.doi.org/10.1017/S0016672300017183

Abstract

A population with N monoecious individuals, and having two alleles, is considered. The problem of calculating the fixation probability of a particular allele under random fluctuation of selection intensities is re-examined, employing finite Markov chain methods. An approximate but general expression for this probability is obtained and the results obtained by previous workers are shown to be special cases of this result.

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